The attached files has the instructions as well as breakdown on how to answer. Essay

The attached files has the instructions as well as breakdown on how to answer. Please use appropriate information which answers the question.
Please only use reliable articles/journals and websites. NHS/Cancer.org etc are do not come under professional sourcesPlease only take this order if you have a good background knowledge in biology/biochemistry and understand what is the question asking.Main point is to provide detail explanation of biochemical abnormalities of primary and secondary disorder.Minimum 6 references required