An organic disease can be defined as one which involves or affects physiology or bodily organs. A disease in which there is a physiological change to some tissue or organ of the body. Organic disease may also be used to mean a condition that is not caused by an infection. And the organic disease that I choose to discuss is Colorectal cancer is a disease in which cells in the colon or rectum grow out of control. Sometimes it is called colon cancer, for short. The colon is the large intestine or large bowel. The rectum is the passageway that connects the colon to the anus.<\/p>\n
Sometimes abnormal growths, called polyps, form in the colon or rectum. Over time, some polyps may turn into cancer. Screening tests can find polyps so they can be removed before turning into cancer. Screening also helps find colorectal cancer at an early stage, when treatment works best. I\u2019ve chosen this organic disease because this disease has caused a lot of heartache within my family. During my early ages of life my uncle was diagnosed with colorectal cancer I became much more determined to learn about this sickness as a result of everything that happened I was able to see how he\u2019s body was deteriorated and how weak he looked as the day pass, all the food the my aunt give him make him throw up. The chemotherapy let all his hair fall and for the family that was devastated to see someone special and how his body was changing as day passed.<\/p>\n
The name of the disease or disorder. Some diseases have multiple names that should be included. According to Colon cancer goes or doesn\u2019t to several names and explain the definition. <\/p>\n
Bowel cancer is also called colorectal cancer. It affects the large bowel, which is made up of the colon and rectum<\/p>\n
How the disease or disorder affects the individual who has it.Are there multiple components to this disease? Some people with colon or rectal cancer may have long lasting trouble with chronic diarrhea, going to the bathroom frequently, or not being able to hold their stool. Some may also have problems with numbness or tingling in their fingers and toes (peripheral neuropathy) from chemo they received.<\/p>\n
Half of adults with cancer require assistance to perform instrumental ADLs. The most commonly affected ADLs include walking and transfers, housework, shopping and transportation. <\/p>\n
For example, if you are doing a disease such as hepatitis, you must cover the 5 different types that exist.<\/p>\n
Types of cancers in the colon and rectum<\/p>\n
Adenocarcinoma is the most common type of colorectal cancer. Adenocarcinomas develop in the cells that make the mucus that lubricates the inside of the colon or rectum. If you\u2019re diagnosed with colorectal cancer, it is most likely adenocarcinoma.<\/p>\n
There are less common types of tumors that can start\/occur in the colon or rectum:<\/p>\n
Gastrointestinal stromal tumors (GISTs) \u2013 cancer that starts in special cells inside the wall of the colon<\/p>\n
Carcinoid tumors \u2013 cancer that starts in hormone-making cells inside the intestine<\/p>\n
Lymphomas \u2013 cancer that primarily starts in the lymph nodes, but can also start in the colon, rectum or other organs<\/p>\n
Sarcomas \u2013 cancer that starts in the blood vessels, muscle layers or other connective tissues, in the wall of the colon or rectum<\/p>\n
Colorectal cancer is described in 5 stages ranging from 0 to IV (4), with stage IV (4) being the most severe. Some stages can also be broken down further into substages (A, B, or C).<\/p>\n
Stage I (1) colorectal cancer<\/p>\n
In stage I colon or rectal cancer, cancer has formed in the mucosa (innermost layer) of the colon or rectum wall and has spread to the submucosa (layer of tissue next to the mucosa) or to the muscle layer of the colon or rectum wall.<\/p>\n
Stage II (2) colorectal cancer<\/p>\n
Stage II colon or rectal cancer is divided into stages IIA, IIB, and IIC.<\/p>\n
In stage IIA<\/p>\n
Cancer has spread through the muscle layer of the colon or rectum wall to the serosa (outermost layer) of the colon or rectum wall.<\/p>\n
In stage IIB<\/p>\n
Cancer has spread through the serosa (outermost layer) of the colon or rectum wall to the tissue that lines the organs in the abdomen (visceral peritoneum).<\/p>\n
In stage IIC<\/p>\n
Cancer has spread through the serosa (outermost layer) of the colon or rectum wall to nearby <\/p>\n
organs.<\/p>\n
Stage III (3) colorectal cancer<\/p>\n
Stage III is divided into stages IIIA, IIIB, and IIIC.<\/p>\n
In Stage IIIA<\/p>\n
Cancer has spread through the mucosa (innermost layer) of the colon or rectum wall to the submucosa (layer of tissue next to the mucosa) or to the muscle layer of the colon or rectum wall. Cancer has spread to 1 to 3 nearby lymph nodes, or cancer cells have formed in tissue near the lymph nodes.<\/p>\n
Or stage IIIA can be<\/p>\n
Cancer has spread through the mucosa (innermost layer) of the colon or rectum wall to the submucosa (layer of tissue next to the mucosa). Cancer has spread to 4 to 6 nearby lymph nodes.<\/p>\n
In stage IIIB<\/p>\n
Cancer has spread through the muscle layer of the colon or rectum wall to the serosa (outermost layer) of the rectum wall or has spread through the serosa to the tissue that lines the organs in the abdomen (visceral peritoneum). Cancer has spread to 1 to 3 nearby lymph nodes, or cancer cells have formed in tissue near the lymph nodes.<\/p>\n
Or stage IIIB can be<\/p>\n
Cancer has spread to the muscle layer or to the serosa (outermost layer) of the colon or rectum wall. Cancer has spread to 4 to 6 nearby lymph nodes.<\/p>\n
Or stage IIIB can be<\/p>\n
Cancer has spread through the mucosa (innermost layer) of the colon or rectum wall to the submucosa (layer of tissue next to the mucosa) or to the muscle layer of the colon or rectum wall. Cancer has spread to 7 or more nearby lymph nodes.<\/p>\n
In stage IIIC<\/p>\n
Cancer has spread through the serosa (outermost layer) of the colon or rectum wall to the tissue that lines the organs in the abdomen (visceral peritoneum). Cancer has spread to 4 to 6 nearby lymph nodes.<\/p>\n
Or stage IIIC can be<\/p>\n
Cancer has spread through the muscle layer of the colon or rectum wall to the serosa (outermost layer) of the rectum wall or has spread through the serosa to the tissue that lines the organs in the abdomen (visceral peritoneum). Cancer has spread to 7 or more nearby lymph nodes.<\/p>\n
Or stage IIIC can be<\/p>\n
Cancer has spread through the serosa (outermost layer) of the colon or rectum wall to nearby organs. Cancer has spread to 1 or more nearby lymph nodes, or cancer cells have formed in tissue near the lymph nodes.<\/p>\n
Stage IV (4) colorectal cancer<\/p>\n
Stage IV is divided into stages IVA, IVB, and IVC.<\/p>\n
In stage IVA<\/p>\n
Cancer has spread to 1 area or organ that is not near the colon or rectum, such as the liver, lung, ovary, or a distant lymph node.<\/p>\n
In stage IVB<\/p>\n
Cancer has spread to more than 1 area or organ that is not near the colon or rectum, such as the liver, lung, ovary, or a distant lymph node.<\/p>\n
In stage IVC<\/p>\n
Cancer has spread to the tissue that lines the wall of the abdomen and may have spread to other areas or organs<\/p>\n
Is there a genetic component to the disease?<\/p>\n
About 5% of people who develop colorectal cancer have inherited gene changes (mutations) that cause family cancer syndromes and can lead to them getting the disease.<\/p>\n
The most common inherited syndromes linked with colorectal cancers are Lynch syndrome (hereditary non-polyposis colorectal cancer, or HNPCC) and familial adenomatous polyposis (FAP), but other rarer syndromes can increase colorectal cancer risk, too.<\/p>\n
Give information regarding the genes involved. Colon cancer is one of the most common inherited cancer syndromes known. Among the genes found to be involved in colorectal cancer are: MSH2 and MSH6 both on chromosome 2 and MLH1, on chromosome 3. Normally, the protein products of these genes help to repair mistakes made in DNA replication. If the MSH2, MSH6, and MLH1 proteins are mutated and therefore don’t work properly, the replication mistakes are not repaired, leading to damaged DNA and, in this case, colon cancer.<\/p>\n
Explain how the disease affects the body.<\/p>\n
Pain areas: in the abdomen<\/p>\n
Gastrointestinal: blood in stool, change in bowel habits, constipation, narrow stools, or passing excessive amounts of gas<\/p>\n
Whole body: anemia or fatigue<\/p>\n
Also common: abdominal discomfort or weight loss<\/p>\n
Provide descriptions.Is there something special about this disease that has not been seen with other diseases? What this diseases has in special according to other cancer diseases is that a person with a cancer on stage____________ they have to perform a colostomy <\/p>\n
How many individuals in the population are affected? <\/p>\n
Almost 10 Million people die from cancer annually<\/p>\n
Cancer is one of the world\u2019s largest health problems. The Global Burden of Disease estimates that 9.56 million people died prematurely as a result of cancer in 2017. Every sixth death in the world is due to cancer.2<\/p>\n
The Global Burden of Disease is a major global study on the causes and risk factors for death and disease published in the medical journal The Lancet.3<\/p>\n
Cancer is a particularly common cause of death in richer countries where people are less likely to die of infectious diseases and causes of deaths that lead to very early deaths for people in poverty.<\/p>\n
The chart is shown for the global total, but can be explored for any country or region using the \u201cchange country\u201d toggle. Switching to one of the richer countries shows that the share of deaths attributed to cancer is higher.<\/p>\n
Because cancer is one of the leading causes of death, it is one of the world\u2019s most pressing problems to make progress against this disease.<\/p>\n
Provide statistics. How did this disease affect you or your family? If no one is affected, then explain why you picked this disease.<\/p>\n
Bibliography\/ Reference <\/p>\n
\u201cColon Cancer.\u201d Mayo Clinic, Mayo Foundation for Medical Education and Research, 8 Oct. 2022, https:\/\/www.mayoclinic.org\/diseases-conditions\/colon-cancer\/symptoms-causes\/syc-20353669.<\/p>\n
Roser, Max, and Hannah Ritchie. \u201cCancer.\u201d Our World in Data, 3 July 2015, https:\/\/ourworldindata.org\/cancer.<\/p>\n
Copyright \u00a9 2022 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. All rights reserved.<\/p>\n
This site is intended only for residents of the United States, its territories, and Puerto Rico.<\/p>\n
US-OVC-00343 12\/21. U.S. National Library of Medicine. (n.d.). National Center for Biotechnology Information. Retrieved November 26, 2022, from https:\/\/www.ncbi.nlm.nih.gov\/.<\/p>\n","protected":false},"excerpt":{"rendered":"
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