Week 4 Discussion Forum77 unread replies.77 replies.Complete your Week 4 discussion prompt by Wednesday, 11:59pm with a minimum of 300 words and minimum 1 reference in APA format. TWO replies are required by Sunday, 11:59pm. Each reply should have a minimum of 50 words and have 1 reference in APA format.
You work for a pharmaceutical company where you are assigned the task of creating new drug therapies to treat thyroid disorders such as hyperthyroidism (high levels of T3 and T4) and hypothyroidism (low levels of T3 and T4). Your team has designed a few drugs, and your job is to identify which drug(s) would be successful in treating thyroid disorders based on your knowledge of thyroid hormone synthesis. Below is the list of drugs your team designed (all of these are hypothetical drugs).
[1] Explain the pathway and negative feedback loop involved in thyroid hormone production beginning with the hypothalamus.
[2] What factors can cause hyperthyroidism? What factors can cause hypothyroidism.
[3] Identify the drug(s) that would be successful in treating hyperthyroidism and hypothyroidism. Explain why and how they would be successful.
Peroxidine: A drug that inhibits thyroid peroxidase from functioning
Cimigine: A drug that inhibits potassium/iodine cotransporter
Iodimine: A drug that inhibits iodinase from functioning
Aldosine: A drug that inhibits production of angiotensinogen from the liver
Aldoramine: A drug that inhibits sodium/iodine cotransporter
Thyromine: A drug that stimulates thyroglobulin production
Be detailed in your explanation and support your answer with facts from your textbook, research, and articles from scholarly journals. In addition, remember to add references in APA format to your posts to avoid plagiarism.
Examples in APA format:
Book: Silverthorn, D.U. (2018). Human Physiology: An Integrated Approach. 8th ed. Pearson.
Webpage: Genetics Home Reference. (2020). Cystic Fibrosis. Accessed on June 3, 2020 from https://ghr.nlm.nih.gov/condition/cystic-fibrosis (Links to an external site.).
Article: Harper, M.R. and Kinney, H.C. (2010). Potential Mechanisms of Failure in the Sudden Infant Death Syndrome. Current Pediatric Reviews. 6(1): 39-47.